Yes, the resistance across the test points connected to the high and low trim pots will change after you solder the jumpers. The Hi and low trim pots need to be measured and set while the jumpers are not soldered together. If you try to measure them while the jumpers are soldered the bias voltage from the opamp will skew the resistance measurement on your meter. You can always adjust them while the jumpers are soldered by listening to your guitar tone and making adjustments accordingly, but if you want to use your meter to set them you’ll have to remove the solder jumpers first.
Thanks for asking.
-Brach